League tables will be settled by a points-per-game format, while promotion and relegation both remain in place.
English Football League clubs approved the EFL board’s plan after a number of alternative options and amendments failed to gain enough support.
League One and League Two teams are due to vote later on Tuesday.
Elite football in England has been suspended since 13 March because of coronavirus, with only the Premier League and Championship so far committing to resuming their seasons later this month.
Talks stalled after at least six clubs in the third tier, including Sunderland, Portsmouth and Ipswich Town, said they wanted to continue the season.
It said the EFL board’s own framework, initially outlined on 21 May, was “overwhelmingly” agreed upon by its 71 clubs.
“The board has endeavoured to listen to all views and alternative approaches but understands that the decisions taken will not be met with universal satisfaction from all clubs,” said EFL chair Rick Parry.
“Today’s outcome ensures that the league and its clubs remains as faithful as possible to the previously agreed regulations and that there is consistency in the approach adopted across the EFL in all divisions if required.”